PD Dr. rer. nat. Stephan E. Wolf
PD Dr. rer. nat. Stephan E. Wolf
http://the-wolf-group.de/
http://biomineralization.de/
Where bio and solids meet: formation mechanisms and cross-scale structure-property relationships of solid inorganic materials formed at the interface to the biological world
- Molecular formation pathways of inorganic, biological, and bio-inspired functional solid-state materials in the light of classical and nonclassical crystallization processes
- Biomimetic synthesis of functional materials, mild and sustainable routes to hybrid and nanostructured materials, with a special focus on liquid/liquid phase separations in water-based inorganic and bioinorganic systems.
- Biosynthesis mechanisms and structure-property-relationships of biominerals
and pathological biominerals.
16.03.2020 | Venia legendi (Materials Science / Werkstoffwissenschaften) – Privatdozent | |
17.07.2009 | PhD in chemistry – Doctor rerum naturalium (summa cum laude) | |
29.09.2005 | Diplom in chemistry (MSc. equivalent) |
Research Positions
03/2022 | Emmy Noether Research Group Leader |
01/2014 – 03/2022 | Juniorprofessor for Materials Science: Biomimetic Materials and Processes (non-tenure track, successful interim evaluation in 2016) |
2013 | Visiting scientist at Max-Planck-Institute for Polymer Chemistry, Mainz, Germany |
2012 | Research Associate at Cornell University, Department of Materials Science and Engineering |
2011 – 2012 | Chercheur postdoctoral at the Centre National de la Recherche Scientifique (CNRS) in the Unité Mixte Recherche UMR6282 Biogéosciences, Université de Bourgogne (Dijon, France) |
2010 | Postdoctoral researcher at Humboldt University Berlin, Germany, in the Institute for Chemistry |
2009 | Postdoctoral researcher at Johannes Gutenberg-University of Mainz (Germany) |
Awards and Honors
Publications
GoogleScholar: s4DH5VYAAAAJ
WebOfScience: 842296
OrCID: 0000-0002-3747-8097
ResearcherID: O-4714-2015
2024
A bicarbonate-rich liquid condensed phase in non-saturated solutions in the absence of divalent cations
In: Frontiers in Bioengineering and Biotechnology 12 (2024), Article No.: 1382047
ISSN: 2296-4185
DOI: 10.3389/fbioe.2024.1382047 , , , , :
2023
The Impact of the Cellular Environment and Aging on Modeling Alzheimer's Disease in 3D Cell Culture Models
In: Advanced Science (2023)
ISSN: 2198-3844
DOI: 10.1002/advs.202205037 , , , , , , :
Evidence for liquid-liquid phase separation during the early stages of Mg-struvite formation
In: Journal of Chemical Physics 159 (2023)
ISSN: 0021-9606
DOI: 10.1063/5.0166278 , , , , , , , , :
In situ mapping of biomineral skeletal proteins by molecular recognition imaging with antibody-functionalized AFM tips
In: Acta Biomaterialia (2023)
ISSN: 1742-7061
DOI: 10.1016/j.actbio.2023.07.028 , , , , , , , , , , , :
2022
The nano- and meso-scale structure of amorphous calcium carbonate
In: Scientific Reports 12 (2022)
ISSN: 2045-2322
DOI: 10.1038/s41598-022-10627-9 , , , , , , , , , , , , , , :
Small-Molecular-Weight Additives Modulate Calcification by Interacting with Prenucleation Clusters on the Molecular Level
In: Angewandte Chemie International Edition (2022)
ISSN: 1433-7851
DOI: 10.1002/anie.202208475 , , , , , , , , , , , :
Influence of Taylor Vortex Flow on the Crystallization of L-Glutamic Acid as an Organic Model Compound
In: Industrial & Engineering Chemistry Research (2022)
ISSN: 0888-5885
DOI: 10.1021/acs.iecr.2c01505 , , , , :
Erratum: Progressive changes in crystallographic textures of biominerals generate functionally graded ceramics (Mater. Adv. (2022) DOI: 10.1039/d1ma01031j)
In: Materials Advances 3 (2022), p. 2598-
ISSN: 2633-5409
DOI: 10.1039/d2ma90020c , , , , , , , , , , , , :
2021
Strong Reduced Graphene Oxide Coated Bombyx mori Silk
In: Advanced Functional Materials (2021)
ISSN: 1616-301X
DOI: 10.1002/adfm.202102923 , , , , , , , , :
Strong, conductive aramid fiber functionalized by graphene
In: Composites Part A-Applied Science and Manufacturing 140 (2021), Article No.: 106161
ISSN: 1359-835X
DOI: 10.1016/j.compositesa.2020.106161 , , , , , , , :
Progressive changes in crystallographic textures of biominerals generate functionally graded ceramics
In: Materials Advances (2021)
ISSN: 2633-5409
DOI: 10.1039/d1ma01031j , , , , , , , , , , , , :
2020
Shape Matters: Crystal Morphology and Surface Topography Alter Bioactivity of Bioceramics in Simulated Body Fluid
In: Advanced Engineering Materials (2020)
ISSN: 1438-1656
DOI: 10.1002/adem.202000044 , , , , , , , , , , :
The multiple stages towards crystal formation of L-glutamic acid
In: Journal of Crystal Growth 544 (2020), Article No.: 125727
ISSN: 0022-0248
DOI: 10.1016/j.jcrysgro.2020.125727 , , , :
2019
Conical nanoindentation allows azimuthally independent hardness determination in geological and biogenic minerals
In: Materials 12 (2019), Article No.: 1630
ISSN: 1996-1944
DOI: 10.3390/ma12101630 , , , :
Bioinspired materials: From living systems to new concepts in materials chemistry
In: Materials 12 (2019), Article No.: 2117
ISSN: 1996-1944
DOI: 10.3390/ma12132117 , , , :
Polymer-functionalised nanograins of Mg-doped amorphous calcium carbonate via a flow-chemistry approach
In: Materials 12 (2019), Article No.: 1818
ISSN: 1996-1944
DOI: 10.3390/ma12111818 , , , , , , , :
Designing Solid Materials from Their Solute State: A Shift in Paradigms toward a Holistic Approach in Functional Materials Chemistry
In: Journal of the American Chemical Society 141 (2019), p. 4490-4504
ISSN: 0002-7863
DOI: 10.1021/jacs.8b13231 , :
Nanoscale deformation mechanics reveal resilience in nacre of Pinna nobilis shell
In: Nature Communications 10 (2019), Article No.: 4822
ISSN: 2041-1723
DOI: 10.1038/s41467-019-12743-z , , , , , , , , , :
Ultra-smooth and space-filling mineral films generated via particle accretion processes
In: Nanoscale Horizons 4 (2019), p. 1388-1393
ISSN: 2055-6756
DOI: 10.1039/c9nh00175a , , , , , , , , :
Mechanical improvement of calcium carbonate cements by: In situ HEMA polymerization during hardening
In: Journal of Materials Chemistry B 7 (2019), p. 3403-3411
ISSN: 2050-750X
DOI: 10.1039/c9tb00237e , , , , :
Phase-specific bioactivity and altered Ostwald ripening pathways of calcium carbonate polymorphs in simulated body fluid
In: RSC Advances 9 (2019), p. 18232-18244
ISSN: 2046-2069
DOI: 10.1039/c9ra01473j , , , , , , :
2017
Universal structure motifs in biominerals: a lesson from nature for the efficient design of bioinspired functional materials
In: Interface Focus 7 (2017), Article No.: 20160120
ISSN: 2042-8901
DOI: 10.1098/rsfs.2016.0120 , , :
Desiccator Volume: A Vital Yet Ignored Parameter in CaCO3 Crystallization by the Ammonium Carbonate Diffusion Method
In: Minerals 7 (2017), Article No.: 122
ISSN: 2075-163X
DOI: 10.3390/min7070122 , :
Enhancement of the Carbothermal Reduction of Hafnium Oxide by Silicon
In: Advanced Engineering Materials 19 (2017), p. 1600377
ISSN: 1438-1656
DOI: 10.1002/adem.201600377 , , , , , :
Challenges and Perspectives of the Polymer-Induced Liquid-Precursor Process: The Pathway from Liquid-Condensed Mineral Precursors to Mesocrystalline Products
In: Van Driessche AES, Kellermeier M, Benning LG, Gebauer D (ed.): New Perspectives on Mineral Nucleation and Growth, Cham: Springer, 2017, p. 43-76
ISBN: 978-3-319-45667-6
DOI: 10.1007/978-3-319-45669-0_3 , :
2016
Structural commonalities and deviations in the hierarchical organization of crossed-lamellar shells: A case study on the shell of the bivalve Glycymeris glycymeris
In: Journal of Materials Research 31 (2016), p. 536-546
ISSN: 0884-2914
DOI: 10.1557/jmr.2016.46 , , , , , :
Nonclassical crystallization in vivo et in vitro (II): Nanogranular features in biomimetic minerals disclose a general colloid-mediated crystal growth mechanism
In: Journal of Structural Biology 196 (2016), p. 260-287
ISSN: 1047-8477
DOI: 10.1016/j.jsb.2016.09.005 , , , :
Nonclassical crystallization in vivo et in vitro (I): Process-structure-property relationships of nanogranular biominerals
In: Journal of Structural Biology 196 (2016), p. 244-259
ISSN: 1047-8477
DOI: 10.1016/j.jsb.2016.07.016 , , , , , , , :
2015
Pseudomorphic transformation of amorphous calcium carbonate films follows spherulitic growth mechanisms and can give rise to crystal lattice tilting
In: Crystengcomm 17 (2015), p. 6831-6837
ISSN: 1466-8033
DOI: 10.1039/c5ce00441a
URL: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000361139300005&KeyUID=WOS:000361139300005 , , , , :
Single nanogranules preserve intracrystalline amorphicity in biominerals
In: Key Engineering Materials 672 (2015), p. 47-59
ISSN: 1013-9826
DOI: 10.4028/www.scientific.net/KEM.672.47 , , , , , :
2014
Synthesis of calcium carbonate biological materials : how many proteins are needed ?
In: Key Engineering Materials 614 (2014), p. 52-61
ISSN: 1013-9826
DOI: 10.4028/www.scientific.net/KEM.614.52 , , , , , , , :
2013
'Shellome': proteins involved in mollusc shell biomineralization – diversity, functions
In: Watabe S, Maeyama K, Nagasawa H (ed.): Recent Advances in Pearl Research, Terrapub, 2013, p. 149-166 , , , , , , , , :
2012
Merging models of biomineralisation with concepts of nonclassical crystallisation: is a liquid amorphous precursor involved in the formation of the prismatic layer of the Mediterranean Fan Mussel Pinna nobilis?
In: Faraday Discussions 159 (2012), p. 433-448
ISSN: 1359-6640
DOI: 10.1039/c2fd20045g
URL: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000310281600024&KeyUID=WOS:000310281600024 , , , , , , , , :
2011
Nonclassical Crystallization of Bivalent Metal Carbonates
Saarbrücken, Germany: SVH Verlag, 2011
ISBN: 978-3838125398 :
Strong Stabilization of Amorphous Calcium Carbonate Emulsion by Ovalbumin: Gaining Insight into the Mechanism of 'Polymer-Induced Liquid Precursor' Processes
In: Journal of the American Chemical Society 133 (2011), p. 12642-12649
ISSN: 0002-7863
DOI: 10.1021/ja202622g
URL: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000294740000061&KeyUID=WOS:000294740000061 , , , , , :
Carbonate-coordinated metal complexes precede the formation of liquid amorphous mineral emulsions of divalent metal carbonates
In: Nanoscale 3 (2011), p. 1158-1165
ISSN: 2040-3364
DOI: 10.1039/c0nr00761g
URL: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000288218300054&KeyUID=WOS:000288218300054 , , , , , , , , :
2010
Formation of silicones mediated by the sponge enzyme silicatein-alpha
In: Dalton Transactions New Horizon of Organosilicon Chemistry (2010), p. 9245–9249
ISSN: 1477-9226 , , , , , , :
2009
- Wang X, Schlossmacher U, Natalio F, Schroeder HC, Wolf SE, Tremel W, Mueller WEG:
Evidence for biogenic processes during formation of ferromanganese crusts from the Pacific Ocean: Implications of biologically induced mineralization
In: Micron 40 (2009), p. 526-535
ISSN: 0968-4328
DOI: 10.1016/j.micron.2009.04.005
URL: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000267515800003&KeyUID=WOS:000267515800003
2008
Reply to "Mirror Symmetry Breaking" of the centrosymmetric CaCO3 crystals with amino acids
In: Angewandte Chemie International Edition 47 (2008), p. 3683-3686
ISSN: 1433-7851
DOI: 10.1002/anie.200800120
URL: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000255791200004&KeyUID=WOS:000255791200004 , , , , , , :
Bioencapsulation of living bacteria (Escherichia coli) with poly(silicate) After transformation with silicatein-alpha gene
In: Biomaterials 29 (2008), p. 771-779
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2007.10.038
URL: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000253014200001&KeyUID=WOS:000253014200001 , , , , , , , , :
Poly(silicate)-metabolizing silicatein in siliceous spicules and silicasomes of demosponges comprises dual enzymatic activities (silica polymerase and silica esterase)
In: Febs Journal 275 (2008), p. 362-370
ISSN: 1742-464X
DOI: 10.1111/j.1742-4658.2007.06206.x
URL: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000252120300014&KeyUID=WOS:000252120300014 , , , , , , , :
Nucleation and growth of CaCO3 mediated by the egg-white protein ovalbumin: A time-resolved in situ study using small-angle neutron scattering
In: Journal of the American Chemical Society 130 (2008), p. 6879-6892
ISSN: 0002-7863
DOI: 10.1021/ja801798h
URL: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000256158200059&KeyUID=WOS:000256158200059 , , , , :
Template Surfaces for the Formation of Calcium Carbonate
In: E. Bäuerlein (ed.): Handbook of Biomineralization, Wiley-VCH Verlag GmbH & Co. KGaA, 2008, p. 209-232
ISBN: 9783527316410
DOI: 10.1002/9783527619443.ch36 , , , , :
Early homogenous amorphous precursor stages of calcium carbonate and subsequent crystal growth in levitated droplets
In: Journal of the American Chemical Society 130 (2008), p. 12342-12347
ISSN: 0002-7863
DOI: 10.1021/ja800984y
URL: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000259139900047&KeyUID=WOS:000259139900047 , , , , :
2007
- Mueller WEG, Schlossmacher U, Eckert C, Krasko A, Boreiko A, Ushijima H, Wolf SE, Trernel W, Mueller IM, Schroeder HC:
Analysis of the axial filament in spicules of the demosponge Geodia cydonium: Different silicatein composition in microscleres (asters) and megascleres (oxeas and triaenes)
In: European Journal of Cell Biology 86 (2007), p. 473-487
ISSN: 0171-9335
DOI: 10.1016/j.ejcb.2007.06.002
URL: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000249057200005&KeyUID=WOS:000249057200005 - Mueller WEG, Eckert C, Kropf K, Wang X, Schlossmacher U, Seckert C, Wolf SE, Tremel W, Schroeder HC:
Formation of giant spicules in the deep-sea hexactinellid Monorhaphis chuni (Schulze 1904): electron-microscopic and biochemical studies
In: Cell and Tissue Research 329 (2007), p. 363-378
ISSN: 0302-766X
DOI: 10.1007/s00441-007-0402-x
URL: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000247932400016&KeyUID=WOS:000247932400016 - Wolf SE, Loges N, Mathiasch B, Panthöfer M, Mey I, Janshoff A, Tremel W:
Phasenselektion von Calciumcarbonat durch die Chiralität adsorbierter Aminosäuren
In: Angewandte Chemie 119 (2007), p. 5716-5721
ISSN: 0044-8249
DOI: 10.1002/ange.200700010 - Wolf SE, Loges N, Mathiasch B, Panthoefer M, Mey I, Janshoff A, Tremel W:
Phase selection of calcium carbonate through the chirality of adsorbed amino acids
In: Angewandte Chemie International Edition 46 (2007), p. 5618-5623
ISSN: 1433-7851
DOI: 10.1002/anie.200700010
URL: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000248330700034&KeyUID=WOS:000248330700034